A user asks: 'What is the capital of France? Also, what is the boiling point of liquid nitrogen? And should I take ibuprofen or acetaminophen for a headache?' What is wrong with an agent that asks three clarifying questions in response?
Answer: Users typically answer only the first question, so subsequent clarifying questions are wasted
The principle is: ask one targeted clarifying question per turn when clarification is needed. Multiple questions result in users answering the first and ignoring the rest, meaning the agent still lacks the information it needed. In this specific case, the questions about France and nitrogen are factual and don't need clarification. The medical question might warrant a single clarifying question about the user's situation.